# Skinbase

##### Mouse Skin and Hair Database

### Welcome to Skinbase

Skinbase, the mutant mouse skin and hair pathology database was established to provide an image reference resource for the histopathology of skin and its associated structures in induced and spontaneous mutations of the laboratory mouse.

The history of mouse genetics is full of examples of the importance of skin and hair phenotypes in the development of our current understanding of the function of many genes and increasingly the mouse has become the model organism of choice for improving our understanding of skin and hair biology in human conditions such as alopecia areata or ichthyosis.

The images presented here are indexed by the common name of the mouse allele. Annotation of the images provides a commentary on the features of the manifestations of the lesion in the skin and associated structures.

Some images of human lesions are included where a mutation of the orthologous gene was demonstrated in the mouse, but for more information about human skin lesions please consult the links on this page.

- Adnexal Glands
- Adrenocortical Dysplasia (acd) Chr8
- Anatomic hair types
- Annotated anatomy of the mouse nail
- Annotated anatomy of the mouse vibrissa
- Aryl Hydrocarbon receptor null (Ahr) Chr12
- Asebia (Stearoyl-Coenzyme A Desaturase 1)
- Beige Lysosomal trafficing regulator (Lyst-bg) Chr13
- Caracul(Krt2-6g-ca) Chr15
- Chronic Proliferative Dermatitis Mutation (cpdm) Chr15
- Crinkled (Edaradd-cr) Chr13
- Depilated (dep) Chr4 38.8cM
- Downless (Edar-dl) Chr10
- Epidermal Growth Factor Receptor (Egfr) Chr11
- Ferrochelatase Deficiency(Fech) Chr18
- Flaky Skin (fsn) Mutant Mouse Chr17
- Fuzzy (fz) Chr1
- Hair cycle
- Matted (ma) and Flaky Tail (ft) Mutant Mice Chr3
- Nails
- Repeated Epilation (Er) Chr4

## Whole slide images

- Normal Skin Histology Vibrissa
- Normal Skin Hair Cycle Histology
- Normal Plucked Hairs
- Hair Interior Defect Mutation Plucked Hairs
- Satin Beige Mutation
- Flaky Skin Mouse Mutation
- Harlequin Ichthiosis Mutation
- Chronic Proliferative Dermatitis Mutation
- Alopecia Areata
- Rhino Mutation
- Ornithine Decarboxylase Transgenic Mouse
- Lanceolate Hair Mutation
- Nude Mouse Mutation
- Asebia Mouse Mutation
- Asebia Mouse Mutation
- Bareskin Mouse Mutation
- B6 Alopecia and Dermatitis
- Transplantable Melanoma
- Transplantable Melanoma
- Cutaneous Papilloma
- Squamous Cell Carcinoma
- Squamous Cell Carcinoma
- Squamous Cell Carcinoma

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