Study meta-data

STUDYID	STOREDB:STUDY1093
CREATEDON	2017-05-19 15:07:14
MODIFIEDON	2017-05-19 15:10:18
UPLOADER	Paul Schofield
DOI	DOI:10.20348/STOREDB/1093

Study details

STUDY NAME
	EPI-CT scan cohort
STUDY STATUS
	Published: Open access to everyone
DATA SHARING POLICY
	Other (specify in 'description')
PRINCIPAL INVESTIGATOR
	Dr Ausrele Kesminiene
SPECIES
	Homo sapiens
SIZE OF COHORT
	100000+
OUTCOME
	Cancer
EXPOSURE CONTEXT
	Medical
INTERNAL OR EXTERNAL EXPOSURE
	External
TYPE OF EXTERNAL EXPOSURE
	X-ray
AGE AT EXPOSURE
	Childhood
EXPOSURE PATTERN
	Protracted
DOSE RATE
	Low
BIOLOGICAL SAMPLE AVAILABLE
	No
STUDY DESCRIPTION
	EPI-CT is a multinational cohort study of children and young adults who have undergone at least one computed tomography (CT) scan before the age of 22 years. It comprises three main parts: 1) an epidemiological cohort study assessing cancer effects of radiation exposure from CT; 2) a dosimetry system to evaluate individual doses and related uncertainty, and supporting dose reduction and optimisa on strategies; 3) a pilot study to evaluate the feasibility of applying diferent biomarkers of hypersensitivity in young patients exposed to low doses from CT. Cohort type: International cohort comprising 1,163,571 patients from BE, DK, FR, DE, NL, NO, ES, SE and GB, who have undergone CT examination. Age/follow-up: - age at exposure: from 0 to 22 years - mean age at the first examination: 10 years, -mean age at the end of cur- rent follow-up: 20 years - follow-up period varies by country and ranges from 1973 to 2015 Data available: -Individual organ doses due to external X-ray irradiation, including uncertainty analy-sis; - cancer incidence; -vital status (except in Ger-many and partially in FR; -socioeconomic status availa-ble in BE, FR, NL, ES and GB -cancer predisposing syndromes available in FR, NL and NO.
PUBMED ID
	26226081