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| STUDY NAME | BIOLOGICAL SAMPLE AVAILABLE | STUDY STATUS | STUDY DESCRIPTION | PUBMED ID | DATA SHARING POLICY | COUNTRY | PRINCIPAL INVESTIGATOR | SPECIES | SIZE OF COHORT | OUTCOME | MEAN DURATION OF FOLLOW-UP (WEEKS) | MELODI RESEARCH PRIORITY | EXPOSURE CONTEXT | INTERNAL OR EXTERNAL EXPOSURE | TYPE OF EXTERNAL EXPOSURE | TYPE OF INTERNAL EXPOSURE | RADIONUCLIDE | AGE AT EXPOSURE | EXPOSURE PATTERN | DOSE RATE | STOREV2 PROJECTID |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| STUDY NAME | BIOLOGICAL SAMPLE AVAILABLE | STUDY STATUS | STUDY DESCRIPTION | PUBMED ID | DATA SHARING POLICY | COUNTRY | PRINCIPAL INVESTIGATOR | SPECIES | SIZE OF COHORT | OUTCOME | MEAN DURATION OF FOLLOW-UP (WEEKS) | MELODI RESEARCH PRIORITY | EXPOSURE CONTEXT | INTERNAL OR EXTERNAL EXPOSURE | TYPE OF EXTERNAL EXPOSURE | TYPE OF INTERNAL EXPOSURE | RADIONUCLIDE | AGE AT EXPOSURE | EXPOSURE PATTERN | DOSE RATE | STOREV2 PROJECTID |
| STOREDB:STUDY1109 Thyroid diseases near Semipalatinsk Nuclear Test Site - Data | No | Restricted: Downloaders have to ask uploader for file access | A description of the study is given in STOREDB:STUDY1008 (http://dx.doi.org/doi:10.20348/STOREDB/1108) . The data stored here include all the EXCEL and SPSS system files that were relevant for prepari ... | Kazakhstan | Nobuo Takeichi, Yoshihiro Noso, Kazbek N. Apsalikov | Homo sapiens | Other activities contributing to low-dose risk research | Environmental | External | gamma | mixed | ||||||||||
| STOREDB:STUDY1108 Thyroid diseases near Semipalatinsk Nuclear Test Site - Description | No | Published: Open access to everyone | Background: Some above ground nuclear tests conducted from 1949 to 1962 at the Semipalatinsk Nuclear Test Site led to radiation exposure of the public. In the frame of the Hiroshima-Semipalatinsk Proj ... | Kazakhstan | Nobuo Takeichi, Yoshihiro Noso, Kazbek N. Apsalikov | Homo sapiens | 1000-9999 | Other activities contributing to low-dose risk research | Environmental | External | gamma | mixed | |||||||||
| STOREDB:STUDY1107 DNA damage accumulation during fractionated low-dose radiation compromises hippocampal neurogenesis | No | Published: Open access to everyone | Genetically-defined mouse strains varying in their DNA repair capacity were exposed to LDR (5x/10x/15x/20x 0.1Gy) and hippocampal dentate gyri from juvenile and adult mice were analyzed 72h, 1, 3 and ... | Germany | Mus musculus | 0-999 | Cognitive effects | 24 | Medical | External | gamma | Juvenile | Acute | High | |||||||
| STOREDB:STUDY1106 acue and chronic TBI irradiation APOE null mice | Yes | Published: Open access to everyone | |||||||||||||||||||
| STOREDB:STUDY1105 The PI3K/Akt/mTOR pathway is a key player in the premature senescence of primary human endothelial cells exposed to chronic radiation | No | Published: Open access to everyone | The etiology of radiation-induced cardiovascular disease (CVD) after chronic exposure to low doses of ionizing radiation is only marginally understood. We have previously shown that a chronic low-dose ... | 23936371 | CC-Attribution Non-Commercial Share Alike | Germany | Dr.Soile Tapio | Homo sapiens | 0-999 | Cardiovascular | 6 | Analysis of mechanisms involved in low dose radiation through use and development of suitable cellular and animal models | Occupational | External | gamma | caesium | Adult | Transitory | Low | ||
| STOREDB:STUDY1104 Quantitative proteomic analysis reveals induction of premature senescence in human umbilical vein endothelial cells exposed to chronic low-dose rate gamma-radiation | No | Published: Open access to everyone | Chronic low-dose ionizing radiation induces cardiovascular disease in human populations but the mechanism is largely unknown. We suggested that chronic radiation exposure may induce endothelial cell s ... | 23349028 | CC-Attribution Non-Commercial Share Alike | Germany | Dr.Soile Tapio | Homo sapiens | 0-999 | Cardiovascular | 12 | Analysis of mechanisms involved in low dose radiation through use and development of suitable cellular and animal models | Occupational | External | gamma | caesium | Adult | Transitory | Low | ||
| STOREDB:STUDY1103 Wildlife Transfer Parameter Database | No | Published: Open access to everyone | This database collates data to provide parameter values for use in environmental radiological assessments to estimate the transfer of radioactivity to wildlife. The database has been updated today (12 ... | United Kingdom | Prof. Nick Beresford | Multiple | 10000-99999 | Environmental | External | mixed | mixed | multiple | |||||||||
| STOREDB:STUDY1102 Materials from LDLensRad London meeting | No | Published: Open access to everyone | Materials and documents from LD Lensrad meeting London 29 January 2018 | CC-Attribution Non-Commercial | United Kingdom | Dr Paul Schofield | |||||||||||||||
| STOREDB:STUDY1100 The role of PPAR alpha in radiation induced heart disease | Yes | Published: Open access to everyone | The PPAR alpha, important regulator of fatty acid metabolism in heart shown to be involved in development of cardiovascular disease. The radiation induced impairment of fatty acid metabolism was obser ... | CC-Attribution Non-Commercial Share Alike | Germany | Dr. Micheal J. Atkinson, Dr.Soile Tapio, Dr.Omid Azimzadeh | Mus musculus | 0-999 | Cardiovascular | 20 | Medical | External | X-ray | X-ray | Adult | Acute | High | ||||
| STOREDB:STUDY1099 Elemental concentrations in representative species of the ICRP's Reference Animals and Plants and associated soils in terrestrial Mediterranean ecosystems in Spain | No | Published: Open access to everyone | Data comprise stable element concentrations in terrestrial Reference Animals and Plants (RAPs) and corresponding whole-body concentration ratios determined in two different Mediterranean ecosystems: a ... | CC-Attribution | Spain | Prof. Nick Beresford | 0-999 | Environmental | |||||||||||||
| STOREDB:STUDY1098 Radioecology data for wildlife and human assessments (UK) | No | Published: Open access to everyone | Data comprise: Observations of Fukushima fallout in Great Britain, Element and radionuclide concentrations in representative species of the ICRP's Reference Animals and Plants and associated soils fro ... | CC-Attribution | United Kingdom | Prof. Nick Beresford | 1000-9999 | Environmental | |||||||||||||
| STOREDB:STUDY1096 Radiation-induced Endothelial Inflammation is Transferred via Secretome to Recipient Cells in a STAT-Driven Process | No | Published: Open access to everyone | Irradiation is the most common treatment of cancer. However, minimizing the normal tissue injury, especially the damage to vascular endothelium, still remains a challenge. This study aimed to analyze ... | CC-Attribution Non-Commercial Share Alike | Germany | Philipp, Jos | Homo sapiens | 0-999 | Cardiovascular | 2 | Examination of the mechanisms and effects of mixed and multi-exposure on cells, tissues, animal models and humans. | Medical | External | X-ray | Adult | Acute | High | ||||
| STOREDB:STUDY1095 Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells | Yes | Restricted: Downloaders have to ask uploader for file access | Radiation is a highly efficient therapy in squamous head and neck carcinoma (HNSCC) treatment. However, local recurrence and metastasis are common complications. Recent evidence shows that cancer-cell ... | CC-Attribution Non-Commercial Share Alike | Germany | Dr.Simone Moertl | Homo sapiens | 0-999 | Cancer | 1 | Identification, development and validation of biomarkers for radiation-induced health (cancer and non-cancer) effects through sound epidemiological studies | Medical | External | gamma | Adult | Acute | High | ||||
| STOREDB:STUDY1094 JANUS database | Yes | Published: Open access to everyone | JANUS is a collection of data and tissue samples from materials made at different US National Laboratories during animal studies done between 1950’s and 1990’s. The Janus experiments, carried out at A ... | 22004930 | CC-Attribution | United States | Prof Gayle Woloschak | Multiple Animal | 100000+ | External | Multiple | ||||||||||
| STOREDB:STUDY1093 EPI-CT scan cohort | No | Published: Open access to everyone | EPI-CT is a multinational cohort study of children and young adults who have undergone at least one computed tomography (CT) scan before the age of 22 years. It comprises three main parts: 1) an epid ... | 26226081 | Other (specify in 'description') | Dr Ausrele Kesminiene | Homo sapiens | 100000+ | Cancer | Medical | External | X-ray | Childhood | Protracted | Low | ||||||
| STOREDB:STUDY1092 Chernobyl Tissue Bank | Yes | Published: Open access to everyone | The Chernobyl Tissue Bank (CTB) was established in 1998 to collect, store and distribute biological samples from patients born on or after 26th April 1967, and resident in the regions of Ukraine and R ... | 24704918 | Other (specify in 'description') | Ukraine | Prof Gerry Thomas | Homo sapiens | 1000-9999 | Cancer | Environmental | Internal | mixed | multiple | Childhood | Transitory | |||||
| STOREDB:STUDY1091 3-generation Exposure Study | Yes | Published: Open access to everyone | The Semipalatinsk nuclear test site (STS) is located approximately 150 km west of the city of Semipalatinsk (now called Semey), and was a major site for nuclear weapons testing by the former Soviet Un ... | Other (specify in 'description') | Kazakhstan | Prof. Kazbek N. Apsalikov | Homo sapiens | 1000-9999 | Transgenerational effects | Environmental | External | mixed | mixed | multiple | Mixed | ||||||
| STOREDB:STUDY1090 Wildlife Transfer Database | No | Published: Open access to everyone | An important factor in assessing the impact of radionuclides on the environment is the means to estimate the transfer of radionuclides to organisms. The WTD was developed to provide an online compilat ... | 23815858 | CC-Attribution | United Kingdom | Prof. David Copplestone | 10000-99999 | Environmental | Internal | Protracted | ||||||||||
| STOREDB:STUDY1089 FREDERICA | No | Published: Open access to everyone | FREDERICA radiation effects database was developed to provide an online compilation of the known effects of ionising radiation on non-human species. FREDERICA contains some 30,000 data entries from 1, ... | 18261830 | Other (specify in 'description') | United Kingdom | Prof. Nick Beresford | 10000-99999 | Environmental | External | |||||||||||
| STOREDB:STUDY1087 Spatial datasets of radionuclide contamination in the Ukrainian Chernobyl Exclusion Zone | Yes | Published: Open access to everyone | Data comprise radionuclide deposition, radioactivity dose measurements, radioactive particle activity and physical characteristic information from soil samples collected within and around the Chernoby ... | CC-Attribution | Ukraine | Valeriy Kashparov | 1000-9999 | Environmental | mixed | Mixed | |||||||||||
| STOREDB:STUDY1086 Single Dose Fe Ion Irradiation Highlights the Radiation Quality Dependent Nature of the Endothelial Cell Response to Ionizing Radiation Exposure | Yes | Published: Open access to everyone | Background and Purpose. Radiotherapy is an essential tool for cancer treatment. In order to spare normal tissue and to reduce the risk of normal tissue complications, particle therapy is a method of c ... | CC-Attribution Non-Commercial | Germany | Omid Azimzadeh | Homo sapiens | 0-999 | Cardiovascular | 1 | Analysis of mechanisms involved in low dose radiation through use and development of suitable cellular and animal models | Occupational | External | X-ray | caesium | Adult | Acute | High | |||
| STOREDB:STUDY1085 Liver and Spleen Tumours in Rats After Injection of Zirconotrast to Which Different Amounts of Th-228/Th-230 Were Added. | No | Published: Open access to everyone | Purpose: To determine the respective roles of the radioactive and chemical component in Thorotrast induced liver and spleen damage. The radioactive Th-228/Th-230 was added to the Zirconotrast Zr-dioxi ... | Germany | Prof. Wesch | Rattus | |||||||||||||||
| STOREDB:STUDY1084 Liver Tumours and Diseases in Rats After Fractionated Neutron Exposure or Injection of Non-radioactive Zirconotrast | No | Published: Open access to everyone | Purpose: To determine the respective roles of the radioactive and chemical component in Thorotrast induced liver damage. The fractionated neutron exposure was to simulate the radioactive, the Zirkonot ... | Germany | Dr. Spiethoff | Rattus | |||||||||||||||
| STOREDB:STUDY1083 Lung Tumours in Rats After Injection of Normal and Th-228 Enriched Thorotrast and Inhalation of Quartz Dusts | No | Published: Open access to everyone | Purpose: To determine whether thoron exhaled from incorporated Thorotrast whose alpha radioactivity was enriched about 25 times in some groups by an addition of Th-228 would cause lung tumours if comb ... | Germany | Prof. Wesch | Rattus | |||||||||||||||
| STOREDB:STUDY1082 Liver and Spleen Tumours in Rats After Injection of Th-230 Enriched Thorotrast | No | Published: Open access to everyone | Purpose: To determine the respective roles of the radioactive and chemical component in Thorotrast gel-induced tumours, alpha radioactivity in Thorotrast was enriched about 50 times by addition of Th- ... | Germany | Prof. Wesch | Rattus | |||||||||||||||
| STOREDB:STUDY1081 Long-term Survival and Tumor Induction After Exposure to High- and Low-LET Radiation | No | Published: Open access to everyone | Purpose: To investigate the influence of sex on long-term survival and tumor induction after exposure to high- and low-LET radiation Status: 1989- 1993 terminated Treatment: Single exposure to 2 ... | Italy | Dr Covelli | Mus musculus | |||||||||||||||
| STOREDB:STUDY1080 Tumours and survival in mice in dependence of age after X-ray and neutron exposure | No | Published: Open access to everyone | Purpose: To determine the RBE in function of the age of the animal. Status: 1984 - 1989, terminated Scientists: V. Di Majo; M. Coppola; S. Rebessi; V. Covelli; Treatment: Single exposure to ... | Italy | Dr Covelli | Mus musculus | |||||||||||||||
| STOREDB:STUDY1079 Myeloid leukaemia and malignant lymphoma in mice after X-ray and neutron exposure | No | Published: Open access to everyone | Purpose: To determine neutron RBE for myeloid leukemia and malignant lymphoma. Status: 1980 - 1984, terminated Treatment: Single exposure to 250 kVp X-rays (133 mGy/min, 1.5 mm HVL) or fission n ... | Italy | Dr Covelli | Mus musculus | |||||||||||||||
| STOREDB:STUDY1078 Myeloid leukaemia and Harderian gland tumours in mice after X-ray and neutron exposure | No | Published: Open access to everyone | Purpose: To determine dose effect relationships for myeloid leukemia and Harderian gland tumors . Status: 1989 - 1992, X-rays terminated Treatment: Single exposure to 250 kVp X-rays (126 mGy/min ... | Italy | Dr Covelli | Mus musculus | |||||||||||||||
| STOREDB:STUDY1077 Late somatic effects in mice after fractionated X-ray and neutron exposure | No | Published: Open access to everyone | Purpose: To determine the dose rate reduction factor and RBE for X-ray and neutron exposure. Status: 1987- ongoing Treatment: Single exposure to 250 kVp X-rays (318 mGy/min, 1.5 mm HVL) and sing ... | Italy | Dr Covelli | Mus musculus | |||||||||||||||
| STOREDB:STUDY1076 Ovarian tumours in mice after X-ray and neutron exposure | No | Published: Open access to everyone | Purpose: To determine the dose relationship and RBE for ovarian murine tumors after X-ray and neutron exposure. Status: 1982 - 1987, terminated, data in ERAD Treatment: Single acute exposure to ... | Italy | Dr Covelli | Mus musculus | |||||||||||||||
| STOREDB:STUDY1075 Lung Tumors following Low-level Radon Exposure at Different Exposure Rates | No | Published: Open access to everyone | Purpose: To study lung cancer risks under conditions simulating the situation in mines and highly exposed homes. Status: 1996-2002, data in ERA. Treatment: Inhalation of radon (0.1-0.3 μm A ... | France | Dr Moncheaux | Rattus | |||||||||||||||
| STOREDB:STUDY1074 Early and Delayed Radiation Effects After Localised Irradiation of Pigs and Rabbits | No | Published: Open access to everyone | Purpose: To study the early radiation-induced necrosis and late radiation-induced fibrosis of skin and underlying tissues after acute localized irradiation with a view to the management of accidental ... | France | Dr Daburon | ||||||||||||||||
| STOREDB:STUDY1073 Regional Gamma Irradiation of Pigs | No | Published: Open access to everyone | Purpose: To study the gastro-intestinal syndrome in pigs exposed to the posterior part of the body with the aim to improve the management of accidental over-exposure in man. Status: 1970 - 1978, te ... | France | Dr Daburon | ||||||||||||||||
| STOREDB:STUDY1072 Brain Damage in 120 Day Old Rats After Single Doses of Co-60 Gamma Irradiation | No | Published: Open access to everyone | Purpose: To study radiation-induced necrosis of the brain and glucose metabolism Status: 1990 - 1992, terminated Treatment: Single exposure of the brain to doses from 0 to 40 Gy of Co-60 gamma i ... | France | Dr Lefaix | Rattus | |||||||||||||||
| STOREDB:STUDY1071 Comparative Radiosensitivity of Developing Brain Structures in the Rat After Gamma Irradiation | No | Published: Open access to everyone | Purpose: To compare the radiosensitivities of proliferative layers of the olfactory bulb (OB), the dentate gyrus of the hippocampus (DG) and the cerebellum (C) Status: 1990 - 1992, terminated Tr ... | France | Dr Ménétrier | Rattus | |||||||||||||||
| STOREDB:STUDY1070 Brain Damage in 90 Day-old Rats Exposed During the Entire Gestation to Co-90 Gamma Rays or Cf-252 Neutrons At Different Dose Rates | No | Published: Open access to everyone | Purpose: To determine the effect of dose rate and relative biological efficiency of neutron vs gamma irradiation for protracted, in utero exposure Status: 1989 - 1992, terminated Treatment: Prot ... | France | Dr Coffigny | Rattus | |||||||||||||||
| STOREDB:STUDY1069 Effects of Prenatal and Postnatal Gamma Irradiation on the Rat Testis | No | Published: Open access to everyone | Purpose: To determine the effect of acute irradiation during gestation and the neonatal period and of protracted exposure during the entire intra-uterine life on adult rat testis: influence of dose ra ... | France | Dr Coffigny | Rattus | |||||||||||||||
| STOREDB:STUDY1068 Tumours and Lifespan in Rats After Treatment with Chemicals | No | Published: Open access to everyone | Purpose: To evaluate the induction or promotion effect of inhalation (or injection) alone and together with -naphthoflavone as promotor. Status: 1977 - 1985, terminated; data in ERAD Treatment: ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1067 Tumours and Lifespan in Rats After Irradiation From Neutrons or Co-60 Gamma Rays and Treatment with Chemicals | No | Published: Open access to everyone | Purpose: To evaluate the influence of cofactors on the effects from Triton neutrons or gamma rays. Status: 1982 - 1985, terminated; data in ERAD except for unavailable groups indicated in italics ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1066 Tumour and Life-time Study on Rats After Acute Neutron Exposure and/or Treatment with Para-dichlorobenzene and Tetrachlorobenzyltoluene | No | Published: Open access to everyone | Purpose: To assess the risks of neutrons in combination with a chemical carcinogen Status: 1986 - 1990, data in ERAD Treatment: Exposure to an about 100 msec flash of fission neutrons from the " ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1065 Tumours and Lifespan in Rats After Irradiation From Different Neutron Sources | No | Published: Open access to everyone | Purpose: To evaluate the dose effect and dose rate relationships for irradiation with different sources of neutrons and compare different sources of neutrons, alpha particles and gamma radiation (a fe ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1064 Tumours and Lifespan in Rats After Gamma Irradiation At Different Ages | No | Published: Open access to everyone | Purpose: To determine the effects of age and the dose rate reduction factor for external gamma irradiation. Status: 1982-1990, terminated, data in ERAD Treatment: Exposure to a low dose rate Co- ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1063 Proteome analysis of irradiated endothelial cells reveals persistent alteration of RhoGDI and NO signalling pathways | Yes | Published: Open access to everyone | Background: Recent epidemiological studies indicate that radiation doses as low as 0.5 Gy may increase the risk of cardiovascular disease. The aim of the present study was to investigate whether this ... | 1 | CC-Attribution Non-Commercial Share Alike | Germany | Omid Azimzadeh | Homo sapiens | 0-999 | Cardiovascular | 14 | Analysis of mechanisms involved in low dose radiation through use and development of suitable cellular and animal models | Medical | External | X-ray | Acute | Low | ||||
| STOREDB:STUDY1062 miRNA profile of extracellular vesicles isolated from bone marrow following in vivo irradiation | No | Restricted: Downloaders have to ask uploader for file access | Male C57Bl/6 mice were irradiated with low and high dose X-ray irradiation. Mice were sacrificed 24 hours later and bone marrow-derived extracellular vesicles were isolated and microRNAs prepared. A m ... | Hungary | Katalin Lumniczky Ph.D. | Mus musculus | 0-999 | Analysis of mechanisms involved in low dose radiation through use and development of suitable cellular and animal models | Medical | External | X-ray | Adult | Acute | High | |||||||
| STOREDB:STUDY1061 Tumours and Lifespan in Rats After High and Low Dose Rate Gamma Irradiation | No | Published: Open access to everyone | Purpose: To determine the dose rate reduction factor for gamma irradiation Status: 1979 - 1985, data in ERAD Treatment: Exposure to a Co-60 gamma source Dosimetry: Ionization chamber Endpo ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1060 Lung Tumours in Monkeys After Inhalation of Actinides | No | Published: Open access to everyone | Purpose: To determine the risks of lung tumors after inhalation of different actinides. Status: 1972 - 1992 Treatment: Inhalation of Pu-239 dioxide (2.3μ AMAD, 0.6μ CMAD) prepared at 1 ... | France | Dr. Michele Morin | ||||||||||||||||
| STOREDB:STUDY1059 Lung Tumours in Rats After Inhalation of Actinides | No | Published: Open access to everyone | Purpose: To assess the risks of lung tumors after inhalation of different alpha-emitting actinides and help to understand the problem of "hot spots" Status: 1965 - 1975, terminated; data in ERAD. ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1058 Lung and Sinus Tumours in Rats After Inhalation or Topical Injection of Ce-144 and Treatment with Different Cofactors | No | Published: Open access to everyone | Purpose: To determine the cancer risks from beta-emitters after inhalation or, to simulate uptake from wounds, after injection of radioactive particles into the leg, the sinus or the maxillary bone an ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1056 Biomaterial from 6 animal experiments conducted at SUBI | Yes | Published: Open access to everyone | An overview is given on biomaterial from six selected animal experiments carried out at SUBI, Russia. These experiments were, ordered by SUBI’s contract numbers: - Contract 75311: “Tritium oxide effe ... | Russia | Eduard Lubchansky | Internal | |||||||||||||||
| STOREDB:STUDY1055 Lung Tumours in Rats After Inhalation of Radon and Treatment with Different Cofactors | No | Published: Open access to everyone | Purpose: To determine the risks of lung tumors after inhalation of radon in combination with treatment with various cofactors. Status: 1973- ongoing; data in ERAD Treatment: Inhalation of radon ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1054 Lung Tumours in Rats After Inhalation of Radon and Application of Different Minerals | No | Published: Open access to everyone | Purpose: To determine the risks of lung tumors after radon inhalation together with various minerals Status: 1968- 1984, terminated; data in ERAD except those indicated in red Treatment: Inhalat ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1053 A dose-dependent perturbation in cardiac energy metabolism is linked to radiation-induced ischemic heart disease in Mayak nuclear workers | No | Published: Open access to everyone | Epidemiological studies show a significant increase in ischemic heart disease (IHD) incidence associated with total external gamma-ray dose among Mayak plutonium enrichment plant workers. Our previous ... | 27391067 | CC-Attribution Share Alike | Germany | Soile Tapio | Homo sapiens | 0-999 | Cardiovascular | Identification, development and validation of biomarkers for radiation-induced health (cancer and non-cancer) effects through sound epidemiological studies | Occupational | Internal | gamma | alpha | Adult | Protracted | Low | |||
| STOREDB:STUDY1052 Lung Tumours in Rats After Inhalation of Radon and Co-carcinogenic Factors | No | Published: Open access to everyone | Purpose: To determine the risks of lung tumors after inhalation of radon together with co-carcinogens Status: 1976 - 1982, data in ERAD except for groups indicated in red Treatment: Inhalation o ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1051 Lung Tumours in Rats After Inhalation of Radon and Mine Polluants or Tobacco | No | Published: Open access to everyone | Purpose: To determine the risks of lung tumors after radon inhalation together with tobacco, soot or gases Status: 1972 - 1982, terminated; data in ERAD except for groups indicated in red Treatm ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1050 Lung tumours in rats after inhalation of radon | No | Published: Open access to everyone | Purpose: To determine the risks of lung tumors after radon inhalation. Status: 1968-1992, terminated; data in ERAD except for groups indicated in red Treatment: Inhalation of radon (0.1-0.3 _ ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1049 Combined controls from Sprague Dawley and Wistar rats | No | Published: Open access to everyone | Purpose: Combined controls from all the different groups carried out over a period of 20 years. Status: 1970 - ongoing, data in ERAD Endpoints: Life-span study (spontaneous death) with macroscop ... | France | Dr. Michele Morin | Rattus | |||||||||||||||
| STOREDB:STUDY1047 Lung Cancer in Rats Exposed to Radon/Radon Daughters | No | Published: Open access to everyone | Purpose: To determine the risk of radon at low levels and to determine the effects of confounding factors which act in exposure to radon in mines vs. that in homes. Status: 1992- ongoing, all expos ... | United Kingdom | Dr. Collier | Rattus | |||||||||||||||
| STOREDB:STUDY1046 Effect of Paternal Exposure to Pu-239 on the Incidence of Cancer | No | Published: Open access to everyone | Purpose: To determine whether internal contamination with Pu-239 increases the incidence of cancer, in particular leukemias, in the F1 generation of CBA mice. Status: 1993 - ongoing Treatment: I ... | United Kingdom | Dr. Jeremy Kellington | Mus musculus | |||||||||||||||
| STOREDB:STUDY1045 Effects of Radiation Quality on the Induction of Leukaemia in CBA/CA Mice | No | Published: Open access to everyone | Purpose: To study the induction of myeloid leukaemias in mice following the administration of fused aluminosilicate particles (FAP) incorporating aloha- and beta-emitting radionuclides. This informati ... | United Kingdom | Dr. Jeremy Kellington | Mus musculus | |||||||||||||||
| STOREDB:STUDY1044 Effects of Alpha and Beta Emitters in Lung | No | Published: Open access to everyone | Purpose: To determine the relative biological effectiveness (RBE) of inhaled, insoluble alpha- and beta-emitting radionuclides with respect to late carcinogenic effects. Status: 1990 - 1994 Trea ... | United Kingdom | Dr. Jeremy Kellington | Mus musculus | |||||||||||||||
| STOREDB:STUDY1043 Life-span Study of the Induction of Lung Tumours in CBA/Ca Mice by Pu-239 Dioxide | No | Published: Open access to everyone | Purpose: To investigate the processes preceding and accompanying Pu-induction of lung tumours in mice and to compare histological and site characteristics of mouse tumours with those in man with a vie ... | United Kingdom | Dr. Nick Priest | Mus musculus | |||||||||||||||
| STOREDB:STUDY1042 Combined effects of Pu-239 Dioxide and Cigarette Smoke on the Production of Lung Tumours in the Mouse | No | Published: Open access to everyone | Purpose: To determine whether cigarette smoke and Pu-239 dioxide act synergistically with respect to the production of lung tumours in CBA/Ca mice. Status: 1987 - 1991, terminated Treatment: Act ... | United Kingdom | Dr. Nick Priest | Mus musculus | |||||||||||||||
| STOREDB:STUDY1041 SUBI tritium exposed Wistar rats | Yes | Restricted: Downloaders have to ask uploader for file access | Information on data and biological material from 224 Wistar rats held at Southern Urals Biophysics Institute of the Federal Medical Biological Agency Ozyersk, Russian Federation Responsible scie ... | CC-Attribution Non-Commercial | Russia | K.N. Muksinova | Rattus norvegicus | 0-999 | Other activities contributing to low-dose risk research | Internal | beta | Protracted | |||||||||
| STOREDB:STUDY1040 High-dose ionising radiation affects TGF beta and PPAR alpha signalling pathways 40 weeks after local heart irradiation in C57BL/6J mice | No | Published: Open access to everyone | Epidemiological data from radiotherapy of thoracic and chest wall tumours show the damaging effect of ionising radiation on heart and vasculature. The long-term impairment of heart function and struct ... | CC-Attribution Non-Commercial Share Alike | Germany | Dr. Omid Azimzadeh | Mus musculus | 0-999 | Cardiovascular | 40 | Identification of specific metabolic pathways and tissue biomarkers related to radiation specific tissue responses. | Medical | External | X-ray | Gamma | Adult | Acute | High | |||
| STOREDB:STUDY1039 Low-dose radiation differentially regulates protein acetylation and histone deacetylase expression in human coronary artery endothelial cells | No | Published: Open access to everyone | Ionizing radiation induces cardiovascular disease, the endothelium being the main target. The exact mechanism of the damage is unclear but the involvement of multiple signaling pathways is probable. R ... | CC-Attribution Non-Commercial No Derivatives | Germany | Dr. Soile Tapio | Homo sapiens | 0-999 | Cardiovascular | 1 | Analysis of mechanisms involved in low dose radiation through use and development of suitable cellular and animal models | Internal | Gamma | Acute | |||||||
| STOREDB:STUDY1038 Mayak Nuclear Workers; proteomics on left ventricle | Yes | Published: Open access to everyone | A Dose-dependent Perturbation in Cardiac Energy Metabolism is Linked to Radiation-induced Ischemic Heart Disease in Mayak Nuclear Workers Background - Epidemiological studies show a significant inc ... | CC-Attribution Non-Commercial | Germany | Dr. Soile Tapio | Homo sapiens | 0-999 | Cardiovascular | 150 | Identification of specific metabolic pathways and tissue biomarkers related to radiation specific tissue responses. | Occupational | External | X-ray | Gamma | Adult | Protracted | Low | |||
| STOREDB:STUDY1037 Semipalatink Nuclear Test Site 3-generation study | Yes | Restricted: Downloaders have to ask uploader for file access | A description of the study is given here: http://www.concert-h2020.eu/~/media/Files/Concert/AIR2/Infrastructures_AIR2_Bulletin_5_March_2016.pdf?la=en , page 3 Examples from the EXCEL spreadsheets w ... | CC-Attribution Non-Commercial | Kazakhstan | Dr. Alexandra Lipikhina | Homo sapiens | 1000-9999 | Other activities contributing to low-dose risk research | Environmental | External | ||||||||||
| STOREDB:STUDY1036 Wismut Uranium Miners – Cohort | No | Restricted: Downloaders have to ask uploader for file access | The German uranium miners cohort study (Wismut cohort) is the largest single cohort study worldwide of miners exposed to radon and its progeny and is being conducted by the Federal Office for Radiatio ... | 25267854 | Germany | Michaela Kreuzer; (Bernd Grosche, Florian Dufey) | Homo sapiens | 10000-99999 | |||||||||||||
| STOREDB:STUDY1034 Wismut Uranium Miners - Biobank | Yes | Restricted: Downloaders have to ask uploader for file access | The German uranium miners cohort study (Wismut cohort) is the largest single cohort study worldwide of miners exposed to radon and its progeny and is being conducted by the Federal Office for Radiatio ... | Germany | Dr. Maria Gomolka | Homo sapiens | 0-999 | 28 | |||||||||||||
| STOREDB:STUDY1029 Wick Data | No | Restricted: Downloaders have to ask uploader for file access | Ra-224 patients treated for ankylosing spondylitis; Germany | Germany | Dr Bernd Grosche | Homo sapiens | 3 | ||||||||||||||
| STOREDB:STUDY1028 Radiobiology studies at SCK-CEN (publications) | No | Restricted: Downloaders have to ask uploader for file access | Belgium | Prof Sarah Baatout | Mus musculus | 64 | |||||||||||||||
| STOREDB:STUDY1027 Radiobiology studies at SCK-CEN (data) | No | Restricted: Downloaders have to ask uploader for file access | Belgium | Prof Sarah Baatout | Mus musculus | Environmental | Acute | High | 66 | ||||||||||||
| STOREDB:STUDY1026 Radiobiology studies at SCK-CEN (samples) | Yes | Restricted: Downloaders have to ask uploader for file access | Belgium | Prof Sarah Baatout | Mus musculus | Environmental | Acute | High | 65 | ||||||||||||
| STOREDB:STUDY1025 Radiobiology studies at SCK-CEN (cell lines) | No | Restricted: Downloaders have to ask uploader for file access | Belgium | Prof Sarah Baatout | Environmental | Acute | 67 | ||||||||||||||
| STOREDB:STUDY1024 Rotterdam mouse study - synaptogenesis | No | Published: Open access to everyone | Germany | Stefan J. Kempf | Mus musculus | 51 | |||||||||||||||
| STOREDB:STUDY1023 NMRI low dose total body liver study | No | Published: Open access to everyone | Proteomic analysis of long-term and short-term effects of low dose ionizing radiation on NMRI mice livers. | CC-Attribution Non-Commercial | Germany | Mr. Mayur Bakshi/ Soile Tapio | Mus musculus | Medical | External | Childhood | Acute | 39 | |||||||||
| STOREDB:STUDY1022 Wound contamination by actinides in the rat | Yes | Published: Open access to everyone | Biokinetics and biodistribution of actinides after contamination of wound in the rat | CC-Attribution Non-Commercial Share Alike | France | Nina griffiths | Rattus norvegicus | 33 | |||||||||||||
| STOREDB:STUDY1021 Japan ApoE proteomics | No | Published: Open access to everyone | Germany | Stefan J. Kempf | 49 | ||||||||||||||||
| STOREDB:STUDY1020 CEREBRAD in utero and postnatal | No | Published: Open access to everyone | Germany | Stefan J. Kempf | Mus musculus | 47 | |||||||||||||||
| STOREDB:STUDY1019 Effects of In-utero low dose irradiation on long-term cardiac proteome | Yes | Published: Open access to everyone | CC-Attribution Non-Commercial Share Alike | Germany | Mr. Mayur Bakshi/ Soile Tapio | Mus musculus | Cardiovascular | Medical | External | In utero | Acute | 57 | |||||||||
| STOREDB:STUDY1018 HUVEC replicative senescence | No | Published: Open access to everyone | Quantitative and integrated proteome and microRNA analysis of endothelial replicative senescence | CC-Attribution Share Alike | Germany | Dr Ramesh Yentrapalli/ Soile Tapio | Homo sapiens | 53 | |||||||||||||
| STOREDB:STUDY1017 German Thorotrast Study (rat data) | No | Restricted: Downloaders have to ask uploader for file access | There are data from four different animal studies with Thorotrast from the years 1975 - 1989 in rats.The study tracks key data, study design, number of animals, a list of responsible scientist and som ... | Germany | G van Kaick | Rattus norvegicus | 6 | ||||||||||||||
| STOREDB:STUDY1016 German Thorotrast Study (human data) | No | Restricted: Downloaders have to ask uploader for file access | The thorium-based radioactive contrast agent Thorotrast (R) was introduced in 1929 and applied worldwide until the 1950s, especially in angiography and arteriography. Due to the extremely long half-li ... | Germany | Prof G van Kaick | Homo sapiens | 1000-9999 | Internal | alpha | thorium | 68 | ||||||||||
| STOREDB:STUDY1015 GENRISK-T (FP6-36495) Iodine131-induced Thyroid Tumours in Mice | Yes | Published: Open access to everyone | To determine the extend to which individual genetic differences influence the risk of developing thyroid cancer after exposure to radiation.Genetic factors can modify susceptibility to the carcinogeni ... | Germany | Dr. Claudia Dalke | Mus musculus | 19 | ||||||||||||||
| STOREDB:STUDY1014 Comparative Toxicity and Retention of Am-241, Pu-239, and U-233 in Mice | Yes | Published: Open access to everyone | Aim: To determine the long-term risks from contamination by different alpha emitters Treatment: Nine i.p. injections of Am-241 citrate, Pu-239 citrate or U-233 citrate (the activity was given as 9 inj ... | CC-Attribution Non-Commercial Share Alike | United Kingdom | Dr Michele Ellender | Mus musculus | 11 | |||||||||||||
| STOREDB:STUDY1013 CEREBRAD VMB | No | Published: Open access to everyone | Germany | Stefan J. Kempf | Mus musculus | 46 | |||||||||||||||
| STOREDB:STUDY1012 CEREBRAD in vitro and in vivo brain | No | Published: Open access to everyone | HT22 cells were irradiated with 0 Gy, 0.5 Gy, 1.0 Gy and 4.0 Gy follwed by mass spectrometry-based analysis 4 hours and 24 hours post irradition. NMRI mice were irradiated with 0 Gy or 1 Gy followed b ... | Germany | Stefan J. Kempf | Mus musculus | 38 | ||||||||||||||
| STOREDB:STUDY1011 CEREBRAD hippocampus cortex NMRI | Yes | Published: Open access to everyone | Germany | Stefan J. Kempf | Mus musculus | Cognitive effects | Medical | External | Childhood | Acute | 29 | ||||||||||
| STOREDB:STUDY1010 Budapest | No | Published: Open access to everyone | Germany | Stefan J. Kempf | Mus musculus | 48 | |||||||||||||||
| STOREDB:STUDY1009 FFPE qualitative proteomics | No | Published: Open access to everyone | Formalin-fixed paraffin embedded (FFPE) tissue has recently gained interest as an alternative to fresh/frozen tissue for retrospective protein biomarker discovery. However, during the fixation process ... | CC-Attribution | Germany | Dr. Omid Azimzadeh | 2 | ||||||||||||||
| STOREDB:STUDY1008 Lung tumours in rats after inhalation of MOX (ASTI) | Yes | Restricted: Downloaders have to ask uploader for file access | CC-Attribution Non-Commercial Share Alike | France | Nina griffiths | Rattus norvegicus | Cancer | Juvenile | Acute | 31 | |||||||||||
| STOREDB:STUDY1007 Osteosarcoma in rats after intravenous plutonium citrate injection (ANE) | Yes | Restricted: Downloaders have to ask uploader for file access | Induction osteosarcomas following iv plutonium citrate in the rat | CC-Attribution Non-Commercial Share Alike | France | Nina griffiths | Rattus norvegicus | 32 | |||||||||||||
| STOREDB:STUDY1006 Acute low-dose effects in hippocampus and cortex (CEREBRAD) | No | Published: Open access to everyone | Germany | Stefan J. Kempf | Mus musculus | 43 | |||||||||||||||
| STOREDB:STUDY1005 Lung tumour induction after Pu or Np inhalation | Yes | Published: Open access to everyone | Data on ERA | CC-Attribution Non-Commercial Share Alike | France | Nina griffiths/ N. Dudoignon | Rattus norvegicus | Cancer | Internal | Juvenile | Protracted | 34 | |||||||||
| STOREDB:STUDY1004 Does acetylation control the low-dose radiation response in endothelial cells? | No | Published: Open access to everyone | SummaryReversible lysine acetylation is a frequent posttranslational protein modification that regulates a broad array of signaling and metabolic pathways. We have shown previously that a radiation do ... | Germany | Dr Zarko Barjaktarovic | 69 | |||||||||||||||
| STOREDB:STUDY1003 Acetylome microvascular cells | No | Published: Open access to everyone | CC-Attribution Non-Commercial Share Alike | Germany | Dr Zarko Barjaktarovic | Homo sapiens | 50 | ||||||||||||||
| STOREDB:STUDY1001 Local high-dose cardiac irradiation induces disturbed energy metabolism associated with impaired PPAR alpha activity in C57BL/6 mice | Yes | Published: Open access to everyone | Radiation exposure is associated with a markedly increased risk of cardiac morbidity and mortality with a latency period of several decades. Although different studies have confirmed the damaging effe ... | Germany | Dr. Omid Azimzadeh | Mus musculus | 20 | ||||||||||||||
| STOREDB:STUDY1000 Integrative cross-omics analysis in cardiac endothelial cells unravels mechanisms of long-term radiation-induced vascular dysfunction | No | Published: Open access to everyone | Epidemiological data from radiotherapy patients show the damaging effect of ionising radiation on heart and vasculature. The endothelium is the main target of radiation damage and contributes essentia ... | CC-Attribution | Germany | Dr. Omid Azimzadeh | Mus musculus | 44 |