Study meta-data

STUDYID	STOREDB:STUDY1094
CREATEDON	2017-05-19 15:53:19
MODIFIEDON	2017-05-19 15:53:19
UPLOADER	Paul Schofield
DOI	DOI:10.20348/STOREDB/1094

Study details

STUDY NAME
	JANUS database
STUDY STATUS
	Published: Open access to everyone
DATA SHARING POLICY
	CC-Attribution
COUNTRY
	United States
PRINCIPAL INVESTIGATOR
	Prof Gayle Woloschak
SPECIES
	Multiple Animal
SIZE OF COHORT
	100000+
INTERNAL OR EXTERNAL EXPOSURE
	External
EXPOSURE PATTERN
	Multiple
BIOLOGICAL SAMPLE AVAILABLE
	Yes
STUDY DESCRIPTION
	JANUS is a collection of data and tissue samples from materials made at different US National Laboratories during animal studies done between 1950’s and 1990’s. The Janus experiments, carried out at Argonne National Laboratory from 1972 to 1989 and supported by grants from the US Department of Energy, investigated the effects of neutron and gamma radiation on mouse tissues primarily from B6CF1 mice. Data and paraffin embedded tissues from thousands of mice and dogs exposed to ionizing radiation are available for research. These materials were collected over several decades of DOE funded research. Studies using these materials and information include computational research as well as use of tissues for PCRs, immunohistochemistry, X-ray fluorescence microscopy etc. All of these resources are available for collaborative research with CONCERT projects and may be of interest for several reasons: (a) archival materials include tissues from many thousands of animals exposed to low dose rates or low doses of radiation; (b) data about radiation exposures of these animals is comprehensive, including about (age of first exposure, dose, dose rate, delivery proto- col etc.) as well as animals (gender, species, strain, age at first and final exposure, age at death, health status etc. ).
PUBMED ID
	22004930