STOREDB:STUDY1149 Russian Radiobiological Human Tissue Repository (RHTR) [DOI:10.20348/STOREDB/1149]

Study meta-data


STUDYIDSTOREDB:STUDY1149
CREATEDON2019-05-13 14:02:04
MODIFIEDON2019-05-13 14:02:04
UPLOADERPaul Schofield
DOIDOI:10.20348/STOREDB/1149

Study details


STUDY NAME
Russian Radiobiological Human Tissue Repository (RHTR)
STUDY STATUS
Published: Open access to everyone
DATA SHARING POLICY
Other (specify in 'description')
COUNTRY
Russia
PRINCIPAL INVESTIGATOR
Tamara Azizova
SPECIES
Homo sapiens
SIZE OF COHORT
1000-9999
EXPOSURE CONTEXT
Occupational
INTERNAL OR EXTERNAL EXPOSURE
External
TYPE OF EXTERNAL EXPOSURE
gamma
TYPE OF INTERNAL EXPOSURE
mixed
RADIONUCLIDE
actinide
AGE AT EXPOSURE
Adult
EXPOSURE PATTERN
Protracted
DOSE RATE
Mixed
BIOLOGICAL SAMPLE AVAILABLE
Yes
ECOLOGICAL DATA
No
STUDY DESCRIPTION
. The Russian Radiobiological Human Tissue Repository (RHTR) was established to collect and store biological samples relevant to human health effects of chronic, low-dose radiation exposure (Loffredo et al. 2017). The RHTR enrolled two cohorts between 1951 and 2017: exposed workers at the Mayak facilities and, as controls, local residents who were never occupationally exposed to ionizing radiation. Overall the cohort of Mayak workers comprises 22,377 individuals employed at one of the main Mayak facilities between 1948 and 1982. These samples are annotated with demographic, occupational, dosimetric and medical information. The repository consists of surgical tissues from 900 individuals, autopsy samples from an additional 1000, together with blood samples and DNA from family trios. Both specimens and data are available to the community.
PUBMED ID
27884938