STUDYID | STOREDB:STUDY1149 |
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CREATEDON | 2019-05-13 14:02:04 |
MODIFIEDON | 2019-05-13 14:02:04 |
UPLOADER | Paul Schofield |
DOI | DOI:10.20348/STOREDB/1149 |
STUDY NAME | ||
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Russian Radiobiological Human Tissue Repository (RHTR) | ||
STUDY STATUS | ||
Published: Open access to everyone | ||
DATA SHARING POLICY | ||
Other (specify in 'description') | ||
COUNTRY | ||
Russia | ||
PRINCIPAL INVESTIGATOR | ||
Tamara Azizova | ||
SPECIES | ||
Homo sapiens | ||
SIZE OF COHORT | ||
1000-9999 | ||
EXPOSURE CONTEXT | ||
Occupational | ||
INTERNAL OR EXTERNAL EXPOSURE | ||
External | ||
TYPE OF EXTERNAL EXPOSURE | ||
gamma | ||
TYPE OF INTERNAL EXPOSURE | ||
mixed | ||
RADIONUCLIDE | ||
actinide | ||
AGE AT EXPOSURE | ||
Adult | ||
EXPOSURE PATTERN | ||
Protracted | ||
DOSE RATE | ||
Mixed | ||
BIOLOGICAL SAMPLE AVAILABLE | ||
Yes | ||
ECOLOGICAL DATA | ||
No | ||
STUDY DESCRIPTION | ||
. The Russian Radiobiological Human Tissue Repository (RHTR) was established to collect and store biological samples relevant to human health effects of chronic, low-dose radiation exposure (Loffredo et al. 2017). The RHTR enrolled two cohorts between 1951 and 2017: exposed workers at the Mayak facilities and, as controls, local residents who were never occupationally exposed to ionizing radiation. Overall the cohort of Mayak workers comprises 22,377 individuals employed at one of the main Mayak facilities between 1948 and 1982. These samples are annotated with demographic, occupational, dosimetric and medical information. The repository consists of surgical tissues from 900 individuals, autopsy samples from an additional 1000, together with blood samples and DNA from family trios. Both specimens and data are available to the community. | ||
PUBMED ID | ||
27884938 |