STOREDB:STUDY1176 Bone marrow-derived extracellular vesicles miRNA and bone marrow cell proteome profiling from irradiated CBA/Ca mice [DOI:10.20348/STOREDB/1176]

Study meta-data


STUDYIDSTOREDB:STUDY1176
CREATEDON2023-01-30 09:47:30
MODIFIEDON2023-01-30 09:47:30
UPLOADERKatalin Lumniczky
DOIDOI:10.20348/STOREDB/1176

Study details


STUDY NAME
Bone marrow-derived extracellular vesicles miRNA and bone marrow cell proteome profiling from irradiated CBA/Ca mice
STUDY STATUS
Restricted: Downloaders have to ask uploader for file access
STUDY TYPE
12-06-00 - Bystander effect study
COUNTRY
Hungary
PRINCIPAL INVESTIGATOR
Katalin Lumniczky
SPECIES
Mus musculus
RADONORM RESEARCH PRIORITY
Analysis of mechanisms involved in low dose radiation through use and development of suitable cellular and animal models
EXPOSURE CONTEXT
Medical
INTERNAL OR EXTERNAL EXPOSURE
External
TYPE OF EXTERNAL EXPOSURE
X-ray
AGE AT EXPOSURE
Juvenile
EXPOSURE PATTERN
Acute
BIOLOGICAL SAMPLE AVAILABLE
No
ECOLOGICAL DATA
No
STUDY DESCRIPTION
CBA/Ca mice were irradiated with 0.1Gy or 3Gy X-rays. Extracellular vesicles were isolated from the bon marrow of control and irradiated mice 24 hours after irradiaiton. The miRNA content of extracellular vesicls was stuided by nCounter analysis system. Isolated control bone marrow cells were incubated with bone marrow-derived extracellular vesicles treated and isolated as described above. The proteome of bone marrow cells was analyzed 24 hours aftre treatment and compared to the proteome of directly irradiated bone marrow cells 24 hours after irradiaton.
MEAN DURATION OF FOLLOW-UP (WEEKS)
1

STOREDB:DATASET1256 Proteomic raw data [DOI:10.20348/STOREDB/1176/1256]


Created on:2023-01-30 09:50:50
Modified On:2023-01-30 09:57:04
DATASET NAME
Proteomic raw data
DOIDOI:10.20348/STOREDB/1176/1256
DATASET DESCRIPTION
Proteome profile of bone marrow cells either directly irradiated or treated with bone marrow-derived extracellular vesicles from irradiated mice
MS Raw Data deposited.xlsx

Type:
File size:

Uploaded on: 2023-01-30 10:01:33

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STOREDB:DATASET1255 Nanostring raw data [DOI:10.20348/STOREDB/1176/1255]


Created on:2023-01-30 09:50:00
Modified On:2023-01-30 09:50:00
DATASET NAME
Nanostring raw data
DOIDOI:10.20348/STOREDB/1176/1255
DATASET DESCRIPTION
Extracellular veicles-derived miRNA analysis by the nCounter analysis system
Nanostring raw data deposited.xlsx

Type:
File size:

Uploaded on: 2023-01-30 10:03:03

Download STOREDB:FILE12984