STORE_DB

STUDY NAME
	Bone marrow-derived extracellular vesicles miRNA and bone marrow cell proteome profiling from irradiated CBA/Ca mice
STUDY STATUS
	Published: Open access to everyone

STUDY TYPE
	12-06-00 - Bystander effect study

COUNTRY
	Hungary

PRINCIPAL INVESTIGATOR
	Katalin Lumniczky
SPECIES
	Mus musculus

RADONORM RESEARCH PRIORITY
	Analysis of mechanisms involved in low dose radiation through use and development of suitable cellular and animal models

EXPOSURE CONTEXT
	Medical

INTERNAL OR EXTERNAL EXPOSURE
	External

TYPE OF EXTERNAL EXPOSURE
	X-ray

AGE AT EXPOSURE
	Juvenile

EXPOSURE PATTERN
	Acute

BIOLOGICAL SAMPLE AVAILABLE
	No
ECOLOGICAL DATA
	No
STUDY DESCRIPTION
	CBA/Ca mice were irradiated with 0.1Gy or 3Gy X-rays. Extracellular vesicles were isolated from the bone marrow of control and irradiated mice 24 hours after irradiaiton. The miRNA content of extracellular vesicls was studied by nCounter analysis system. Isolated control bone marrow cells were incubated with bone marrow-derived extracellular vesicles treated and isolated as described above. The proteome of bone marrow cells was analyzed 24 hours after treatment and compared to the proteome of directly irradiated bone marrow cells 24 hours after irradiation.
MEAN DURATION OF FOLLOW-UP (WEEKS)
	1

Created on:2023-01-30 09:50:50
Modified On:2023-01-30 09:57:04

DATASET NAME
	Proteomic raw data
DOI	DOI:10.20348/STOREDB/1176/1256
DATASET DESCRIPTION
	Proteome profile of bone marrow cells either directly irradiated or treated with bone marrow-derived extracellular vesicles from irradiated mice

Type:
File size:

Uploaded on: 2023-01-30 10:01:33

Created on:2023-01-30 09:50:00
Modified On:2023-01-30 09:50:00

DATASET NAME
	Nanostring raw data
DOI	DOI:10.20348/STOREDB/1176/1255
DATASET DESCRIPTION
	Extracellular veicles-derived miRNA analysis by the nCounter analysis system

Type:
File size:

Uploaded on: 2023-01-30 10:03:03